Le yi-8 yeebhiliyoni zeerandi zeThuba loTyalo-mali lwe-VCs kunye nabaSeki abanakho ukungayihoyi

Ixesha elide loQoqosho aluSeyo iNzululwazi yeNzululwazi — Yeyona nto inkulu yoTyalo-mali kule minyaka ilishumi

Ndaweni ethile phakathi kwe-biohacking podcasts kunye neephaneli zegazi ze-400 zeedola, ishishini elisemthethweni letriliyoni yeedola liye lathula. Uqoqosho lwehlabathi elide - olubandakanya yonke into esuka kwi-anti-aging therapeutics kunye nokuxilongwa ngokuchanekileyo kwiiplatifti ze-wellness-tech kunye neziseko zokunakekelwa kwezempilo eziphezulu - kuqikelelwa ukuba idlule i-$ 8 yezigidigidi nge-2030, ngokutsho koqikelelo oluvela kwi-National Academy of Medicine kunye neBhanki yaseMelika yoPhando lweHlabathi. Kumashishini ongxowankulu abajonga i-horizon kudidi olulandelayo-luchaza ithuba, kunye nabaseki abakhangela iimakethi ezinesimo sedemografi esingayi kuyeka, olu luphawu olungcwatywe ngaphakathi kwingxolo yendlela yokuphila kakuhle. Isithuba sobomi obude asiyofashoni. Lutshintsho lwezoqoqosho oluqhutywa ngabantu abalupheleyo, iteknoloji yebhayoloji eqhubela phambili, kunye nesiseko sabathengi abaya kuhlawula phantse nantoni na ukongeza iminyaka esempilweni ebomini babo.

Kutheni i-8 yezigidi zezigidi zeedola ayiyoHype — Amanani angemva koBom obude

Izibalo ezisemva koqoqosho lwexesha elide yidestiny yedemografi. Ngo-2030, yonke i-Baby Boomer e-United States iya kuba ngaphezu kwe-65. Kwihlabathi jikelele, abantu abaneminyaka eyi-60 nangaphezulu baya kufikelela kwi-1.4 yebhiliyoni - phantse kabini inani ukusuka ku-2015. Bangabasebenzisi abasebenzayo ababeka impilo, amandla, kunye nokwandisa iminyaka yabo yemveliso. UMcKinsey uqikelela ukuba abathengi abangaphezulu kwama-60 sele bebalelwa ngaphezulu kwe-50% yokukhula kosetyenziso lulonke kuqoqosho oluphuhlileyo.

Kodwa eli ayilobali nje malunga nabantu abadala. I-Millennials kunye ne-Gen Z ziqhuba intshukumo yezempilo yokukhusela ngokulinganayo. Imarike yezempilo yehlabathi ifikei-$ 5.6 yezigidigidi kwi-2023, kunye ne-subset-specific-specific-long-specific-diagnostics, NAD + supplements, iiklinikhi ze-hormone optimization, iiplatifomu zezempilo eziqhutywa yi-AI-yeyona nto ikhula ngokukhawuleza ngaphakathi kwayo. Inkxaso-mali ye-Venture kwi-startups egxininisekile kwixesha elide yawela i-5.2 yeebhiliyoni zeedola kwi-2023kuphela, ukunyuka kwe-40% ukusuka kunyaka ongaphambili. Iingxowa-mali ezifana neNgxowa-mali ye-Longevity Vision, i-Life Biosciences, kunye ne-Apollo Health Ventures ihambisa amakhulu ezigidi kwindawo, kunye nezikhulu zenkampani ezifana ne-Google (nge-Calico Labs) kunye noJeff Bezos (nge-Altos Labs) baye babeka iibhiliyoni zeedola.

Ukudibana kwe-AI, i-genomics, kunye nobuchwephesha bezempilo yabathengi kucinezela into ebikade iyimijikelo yophando yamashumi eminyaka ukuya kwiminyaka. Unyango olusekelwe kwi-CRISPR lungena kwizilingo zeklinikhi kwizifo ezinxulumene neminyaka. Iimonitha ze-glucose eziqhubekayo, eziye zagcinwa kwi-diabetics, ngoku ziyimveliso yabathengi abaqhelekileyo. Oku kukhawuleziswa kuthetha ukuba umphezulu wotyalo-mali ukhula ngokukhawuleza kunokuba uninzi lweeVCs zinokuwenza imephu.

IiNqaku eziHlanu eziNqolileyo apho iSmart Money ihamba khona

Ayingawo onke amathuba obomi obude adalwe ngokulinganayo. Indawo ibanzi ngokwaneleyo ukubandakanya iilebhu zophando lwamayeza kunye neebhrendi zokongeza ngokuthe ngqo kumthengi - kodwa oyena nkunzi ukrelekrele ugxile kwi-verticals apho ubuchwepheshe budala i-moats ekhuselekayo kunye nengeniso ephindaphindiweyo.

• I-Precision Diagnostics & Biomarkers: Iinkampani ezifana ne-Grail (ukuxilongwa komhlaza kwangaphambili) kunye ne-InsideTracker (uvavanyo lwe-biological age) zakha iiplatifomu ezisekelwe kwi-subscription eguqula igazi lidonsa kwi-intelligence yezempilo eqhubekayo. Icandelo lokuxilonga lilodwa lilindeleke ukuba lifike kwi-98 yeebhiliyoni zeedola ngo-2028.
• I-AI-Powered Discovery Drug Discovery: I-Startups efana ne-Insilico Medicine isebenzise i-AI ukuzisa abaviwa beziyobisi kwi-concept ukuya kwi-Phase I kulingo kwiinyanga ezingaphantsi kwe-18 - inkqubo ethatha iminyaka eyi-4-5 ngokwesiko. Abatyali-mali babona oku njengeyona nto iphezulu-isilingi ethe nkqo kubomi obude.
• Ii-Platforms zokuPhila kwaBathengi: Ukusuka kwiNqanaba leMpilo (ukulungiswa kwe-metabolic) ukuya kwi-Whoop (ukulandelela ukubuyisela), iimpawu ezijongene nomthengi ezijongene nexesha elide zibonisa ukuba abantu baya kuhlawula i-$ 30-50 / ngenyanga kwidatha yezempilo. Amazinga okugcina onyaka ngaphezu kwe-70% enza ezi zoqoqosho ezifana ne-SaaS zingenakunqandwa kwi-VCs.
• Iyeza lokuHlaziywa ngokutsha kunye noNyango: Unyango lwe-stem cell, i-senolytics (iziyobisi ezisusa iiseli ezonakalisiweyo), kunye ne-rapamycin analogues zitshintsha ukusuka kwi-lab curiosities ukuya kwiinyani zeklinikhi. Kulapho ukuphuma kwebhiliyoni yeedola kuya kuvela khona.
• Iiklinikhi zobomi obude kunye neMpilo ye-Concierge: I-Brick-and-mortar idibana ne-biotech. Iinkampani ezifana neFountain Life kunye nePeak Health zinika i-$ 10,000 + yobulungu bonyaka ukuze kuhlolwe impilo kunye nokuphucula. Imarike yezempilo ye-concierge ikhula ngama-25% ngonyaka.

Yintoni abaSeki abangalunganga malunga neMakethi yoKuphila ixesha elide

Kwinkampani nganye esemthethweni yokuphila ixesha elide etsala utyalo-mali olunzima, kukho ezininzi ezithi shwaka ngenxa yokuba abasunguli abaqondi kakuhle ukuguquka kweemarike. Eyona mpazamo ixhaphakileyo kukuphatha ixesha elide njengomdlalo ococekileyo we-biotech. Ngelixa isayensi ibalulekile, iinkampani ezifumana intshukumo ngokukhawuleza zezo zidibanisa ukuthembeka kwezesayensi kunye namava omgangatho wabathengi kunye nokusebenza ngokugqwesileyo. Idatha yakho yeklinikhi ayithethi nto ukuba umthengi wakho akakwazi ukubhukisha idinga, ukulandelela iziphumo zabo, okanye ukufumana ukhathalelo olulandelayo ngaphandle kokungqubuzana.

Impazamo yesibini ebalulekileyo kukujongela phantsi ubunzima bokusebenza. Amashishini ahlala ixesha elide - nokuba ziiklinikhi, iimpawu ezongezelelweyo, okanye iiplatifti zezempilo-zinoqeqesho oluninzi. Bafuna iinkqubo zeCRM zokulawula ubudlelwane besigulane, izibonelelo ze-invoyisi zobulungu beprimiyamu, ukucwangciswa kokuqeshwa kotyelelo oluphindaphindiweyo, iidashbhodi zokuhlalutya ukubonisa iziphumo, kunye neenkqubo ze-HR zokulawula abasebenzi abakhethekileyo kwiindawo ezininzi. Abaseki abazama ukuthunga kunye ezintlanu okanye ezintandathu izixhobo ezingadityaniswanga ngokungenakuthintelwa baphulukana nesantya sokutsala ukusebenza.

Apha kulapho amaqonga afana neMewayz abe ziziseko ezingundoqo kune-software kuphela. Ngeemodyuli ezingama-207 ezidibeneyo ezithatha i-CRM, i-invoyisi, ukubhuka, ukuhlawulwa, i-HR, ulawulo lwezithuthi, kunye nohlalutyo, i-Mewayz inika abasunguli bexesha elide inkqubo yokusebenza edibeneyo ukuqhuba yonke into engeyiyo yeklinikhi yeshishini labo. Endaweni yokutshisa umgaqo weenqwelo-moya kwiimfumba zeteknoloji yaseFrankenstein, abaseki banokusungula, basebenze, kwaye balinganise kwiqonga elinye - ukukhulula inkunzi kunye nokuhoywa kwenzululwazi kunye namava omthengi okwenene ahlula uphawu lwabo.

"Iinkampani zexesha elide eziphumeleleyo aziyi kuba nesayensi engcono kakhulu - ziya kuba nezona zixhobo zokusebenza ezingcono kakhulu. Kwimarike ekhula ngokukhawuleza, abasunguli abacwangcisa kwangaphambili ngabo abalinganisa. Abanye bangcwatywa kwi-spreadsheets kunye nokulandelwa okulahlekileyo ngelixa abakhuphisana nabo bedibanisa. " — Ingqiqo ethatyathwe kudliwano-ndlebe nabaphathi beengxowa-mali zexesha elide kunye nabasebenzi bobugcisa bezempilo.

I-VC Playbook: Indlela abaTyali-mali abaVavanya ngayo iZiqalo zexesha elide

Abatyali-zimali bamaziko abasukeli nje umxholo wobomi obude ngobumfama. Isakhelo sovavanyo sikhule ngokubonakalayo ukusukela kwiintsuku zokuqala zeepitshi ezingacacanga "zokuthintela ukuguga". Inqanaba eliphezulu lanamhlanje le-VCs likhangela izikhombisi ezintathu ezicacileyo: i-recurring revenue mechanics, ingcaciso elawulayo, kunye neziphumo zenethiwekhi yedatha. Iinkampani ezivelisa idatha yezempilo yobunikazi kwisikali - kwaye ziyisebenzisele ukuphucula iziphumo ngokuhamba kwexesha - ziyalela amaxabiso aphezulu kakhulu kuba i-moats yazo inzulu ngayo yonke intsebenziswano yabathengi.

Indawo yolawulo ibaluleke ngokufanayo. I-FDA's eguqukayo isimo sokuguga njengemeko enyangekayo (kunokuba ibe yinkqubo engenakuthintelwa) ivula iingcango ebezitshixiwe amashumi eminyaka. Ulingo lwe-TAME - ukuvavanya i-metformin njengechiza elichasayo - limele isakhelo sokuqala esivunyiweyo se-FDA sokunyanga ukuguga ngokwayo. Iziqalo ezikwindawo phakathi kwale ndlela yolawulo isakhulayo zinenzuzo yesakhiwo kunezo zisebenza kwimimandla engwevu yolawulo.

Uqikelelo lophinda-phindo lubonisa ukuzithemba kwemarike. Iiplatifti zexesha elide zabathengi ziyalela i-12-18x yengeniso yokuphindaphinda kwimijikelo yasemva kwexesha, ethelekiswa nencopho yoqikelelo lwe-SaaS. Iinkampani zokuxilonga ezineemodeli zobhaliso zibona iipremiyamu eziphezulu. Ngokomxholo, i-median ye-SaaS ephindaphindwayo ngo-2024 yahlala malunga ne-6-8x - oko kuthetha ukuba ubomi obude buthengisa ngokuphindwe kabini kwimarike yesoftware ebanzi.

Ukwakha ishishini lexesha elide elinokulinganisa ngokwenyani

Umahluko phakathi kokuqalisa ubomi obude okuphakamisa umjikelezo wembewu kunye nokufikelela kwi-10 yezigidi zeedola ze-ARR ngokuqhelekileyo kuhla kwizigqibo zeziseko zophuhliso ezenziwe kwiinyanga ezili-12 zokuqala. Abaseki abatyala imali kwangethuba kwimisebenzi yoshishino ehlanganisiweyo - ukuhlawula okuzenzekelayo, iirekhodi zabaxumi ezibekwe kwindawo enye, unxibelelwano olucwangcisiweyo, kunye nohlalutyo lwexesha lokwenyani - luhlala lubagqwesa abo bayeke ukuvuthwa kokusebenza.

Qwalasela iklinikhi yokuphila ixesha elide esungulwa kwiimarike ezintathu ngaxeshanye. Ngaphandle kweenkqubo ezidityanisiweyo, indawo nganye iphuhlisa eyayo ukuhamba komsebenzi ukwenzela ukuthatha isigulana, ukuhlawula, ulawulo lwempahla, kunye nokucwangciswa kwabasebenzi. Kwiinyanga ezintandathu, umseki uchitha ixesha elininzi ekucimeni umlilo kunokukhula. Ngeqonga elifana ne-Mewayz ephethe i-backbone yokusebenza - ukusukaukubhukisha kunye ne-CRMukuyai-invoyisi kunye ne-payrollkuzo zonke iindawo - loo msunguli ofanayo uhlala egxininise kwiiprothokholi zeklinikhi, uphuhliso lobambiswano kunye nokuxhaswa ngemali. Iqonga loyilo lwemodyuli lithetha ukuba bavula kuphela izixhobo abazidingayo ekusungulweni nasekukhuliseni njengoko ishishini likhula, ngaphandle kokufuduka kwedatha okanye ukuqeqesha abasebenzi kwakhona.

Obu buchule bokusebenza asiyonto intle ukuba ube nayo kubomi obude — yinto efunekayo kuqala. Ii-VCs ziya zivavanya ukukhula kwe-ofisi yasemva ngexesha lokukhuthala. Ukuqaliswa okuqhutywa kwi-spreadsheets eziqhawulwe kunye neenkqubo zemanuwali zibonisa umngcipheko, kungakhathaliseki ukuba inzululwazi inyanzelisa kangakanani.

Ifestile Ivuliwe — Kodwa Ayizukuhlala Ivuliwe Ngonaphakade

Lonke ithuba lotyalo-mali lokuvelisa linefestile ye-asymmetry ephezulu - ixesha apho imakethi inkulu ngokwaneleyo ukuba ibeyinyani kodwa kwangoko ngokwaneleyo ukuba iinkokeli zodidi khange zithweswe sithsaba. Kubomi obude, loo festile ilungile ngoku. Ukudityaniswa kokuphumelela kwezenzululwazi, imfuno yabathengi, inguqu elawulayo, kunye nokufumaneka kwenkunzi kudale iimeko ebezingekho neminyaka emithathu eyadlulayo.

Kodwa ifestile iyacutha. Njengoko inkunzi yeziko izandyondyo zemvula, iindleko zokufunyanwa kwabathengi ziyenyuka, ifom yokulawula imisele, kunye nenzuzo yokuqala yokuhambisa. Ubomi obude obuqalayo obuqalisa kunye nobukhulu ngokufanelekileyo kwi-2025-2027inokuthi ichaze udidi kumashumi amabini eminyaka ezayo. Abo bafika emva kwexesha baya kukhuphisana ngexabiso kwimarike evuza i-premium positioning.

Kubaseki, isinyanzeliso sicacile: hamba ngokukhawuleza, kodwa yakha smart. Uqoqosho lwexesha elide luvuza abaqhubi abadibanisa amabhongo enzululwazi kunye neziseko zophuhliso lweshishini. Kwi-VCs, umyalezo ungqale ngokulinganayo: i-8 yeetriliyoni zeedola ayiyosilingi - yindawo yokuqala. Njengolwandiso lolwandiso lobomi ukusuka kulangazelelo ukuya kulindelo, yonke imveliso ekufuphi - i-inshurensi, umhlaba, imfundo, ucwangciso lwabasebenzi - iya kuhlengahlengisa ixesha elide, ubomi obunempilo. Iziphumo zokurhweba ziya kudala amathuba otyalo-mali kumashumi eminyaka ezayo.

Umbuzo awungowokuba uqoqosho lwexesha elide luya kuzisa imbuyekezo. Kukuba uyakubekwa ukuba ubabambe xa isenzeka.

Imibuzo Ebuzwa Rhoqo

Kutheni uqoqosho lwexesha elide lujongwa njengethuba le-8 yetriliyoni zeedola?

Uqoqosho lwexesha elide lubandakanya unyango oluchasayo, ukuxilonga ngokuchanekileyo, iiplatifti ze-wellness-tech, kunye neziseko zononophelo eziphezulu. NgokweNational Academy of Medicine kunye neBhanki yaseMelika yoPhando lweGlobal, le marike ilindeleke ukuba idlule kwi-8 yetriliyoni zeedola ngo-2030. Iqhutywa ngabantu abalupheleyo, imfuno yabathengi yokongezwa kwexesha lezempilo, kunye nokuphumelela kwi-biotech, imele enye yee-megatrend ezinkulu ezityalwayo kwi-VCs kunye nabaseki kule minyaka ilishumi.

Ngawaphi amacandelo kubomi obude anikezela ngembuyekezo eyomeleleyo kubatyali-mali?

Amacandelo aphezulu okukhula abandakanya ukuxilonga ngokuchanekileyo, ukufunyanwa kweziyobisi eziqhutywa yi-AI, iyeza lokuvuselela, ubuchwepheshe bokunakekelwa kwabadala, kunye namaqonga okukhusela impilo. Amathuba akwinqanaba lokuqala kuhlalutyo lwe-biomarker kunye neeprothokholi zempilo ezenzelwe umntu zitsala inkunzi enkulu yemali. Abaseki bakha amaqonga anokunyuka adibanisa ubude bexesha elide babekwe kakuhle ukuba babambe isabelo semarike njengoko ukwamkelwa kwabathengi kukhula ngokukhawuleza kwiidemografi.

Ngaba abaseki abangena kwindawo yokuphila ixesha elide bangayilawula njani imisebenzi ngokufanelekileyo?

Iziqalo zobomi obude zijija ukuhamba komsebenzi okuntsonkothileyo - ukusuka kulawulo lwabathengi kunye nentlawulo yokurhuma ukuya kwintengiso yomxholo kunye nohlalutyo. Amaqonga afana Mewayz adibanisa ezi mfuno zibe yi-OS yeshishini elinye elinemodyuli ezingama-207 eziqala kwi-$19/mo, ephelisa imfuno yokuthunganiswa kwezixhobo ezininzi ezahlukeneyo ukuze abaseki bagxile kuphuhliso lwemveliso kunye nonyuso lwengxowa-mali endaweni yokusebenza ngaphezulu.

Ingaba uqoqosho lwexesha elide lufanelekile kuphela kwi-biotech-focused startups?

Akunjalo konke konke. Uqoqosho lwexesha elide lunwenwela ngaphaya kwe-biotech kwimpilo yabathengi, itekhnoloji yokuqina, amaqonga ezempilo yengqondo, isayensi yezondlo, ukusungula inshorensi, kunye neenkonzo zokhathalelo lwabadala. Abaseki be-SaaS, oosomashishini bempilo yedijithali, kunye neemveliso ze-e-commerce ezijolise kubantu abanolwazi lwezempilo banokuzuza kweli gagasi. Naziphi na iingxaki zokusombulula iingxaki ezinxulumene nempilo, uthintelo, okanye iziseko zophuhliso ezigugayo kufuneka zixhamle kolu rhwebo luyandayo.